John O'Brien

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John O’Brien is Professor of Old Age Psychiatry in the Department of Psychiatry at the University of Cambridge. He is a National Institute for Health Research (NIHR) Emeritus Senior Investigator and a Fellow of the UK Academy of Medical Sciences. He is the NIHR Clinical Research Network National Specialty Lead for Dementia.
His main research interests are improving the diagnosis and management of Lewy body dementia and he was Chief Investigator on the DIAMOND-Lewy study. He has been a member of the National Institute for Health and Social Care Excellence (NICE) and several International Dementia Guideline groups.

Professor John O'Brien

John is Professor of Old Age Psychiatry and Head of the Old Age Psychiatry Research Group in the Department of Psychiatry at the University of Cambridge. 
He is a National Institute for Health Research (NIHR) Emeritus Senior Investigator and an elected Fellow of the UK Academy of Medical Sciences. From 2014 to 2024 he was the NIHR National Lead for Dementia in England.

His interests are in the use of brain imaging and other biomarkers in dementia and the diagnosis and management of Lewy Body and vascular dementias. He has been a member of several guideline groups, including the National Institute for Health and Care Excellence (NICE), the British Association of Psychopharmacology, the European Federation of Neurological Sciences and the European Stroke Association. 

He was Chief Investigator on the NIHR-funded DIAMOND-Lewy Programme, which developed evidence-based toolkits to improve the diagnosis and management of Lewy body dementia, both dementia with Lewy bodies and Parkinson’s disease dementia.

John is Professor of Old Age Psychiatry and Head of the Old Age Psychiatry Research Group in the Department of Psychiatry at the University of Cambridge. 
He is a National Institute for Health Research (NIHR) Emeritus Senior Investigator and an elected Fellow of the UK Academy of Medical Sciences. From 2014 to 2024 he was the NIHR National Lead for Dementia in England.

His interests are in the use of brain imaging and other biomarkers in dementia and the diagnosis and management of Lewy Body and vascular dementias. He has been a member of several guideline groups, including the National Institute for Health and Care Excellence (NICE), the British Association of Psychopharmacology, the European Federation of Neurological Sciences and the European Stroke Association. 

He was Chief Investigator on the NIHR-funded DIAMOND-Lewy Programme, which developed evidence-based toolkits to improve the diagnosis and management of Lewy body dementia, both dementia with Lewy bodies and Parkinson’s disease dementia.

Last updated 23 September 2025